Main: Ethcathinone, also known as ethylpropion, is a stimulant drug of the phenethylamine, amphetamine, and cathinone chemical classes. It is an active metabolite of diethylcathinone, to which it acts as a prodrug, and is fully responsible for its effects. Ethcathinone has been identified as an ingredient in both quasi-legal "party pills", and, along with mephedrone, has also been reported as having been sold as "ecstasy" in the Australian city of Cairns.
The pharmacology for ethcathinone appeared alongside other psychostimulants in a paper by Rothman and Baumann in 2006. The predominant two modes of action for ethcathinone is as a moderately active releaser of noradrenaline (EC50 = 99.3 nM); however it is only a relatively weak inhibitor of dopamine reuptake (Ki = 1014 nM). Since diethylcathinone appears to be an inactive prodrug and only becomes active after it has been further metabolized to ethcathinone, it thereby would appear rational to consider that ethcathinone would also be expected to be N-dealkylated upon its consumption to the more active drug cathinone that is more able to reliably stimulate the release of dopamine. However, in contrast to diethylcathinone, ethcathinone is not technically a prodrug since it is already active in its own right.
Ethcathinone, along with mephedrone and flephedrone, was banned in Denmark on December 18, 2008.